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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EEF2K
All Species:
5.76
Human Site:
Y463
Identified Species:
12.67
UniProt:
O00418
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00418
NP_037434.1
725
82144
Y463
P
R
E
H
G
H
S
Y
S
N
R
K
Y
E
S
Chimpanzee
Pan troglodytes
XP_001161085
725
82249
Y463
P
R
E
H
G
H
S
Y
S
N
Q
K
Y
E
S
Rhesus Macaque
Macaca mulatta
XP_001092565
725
82310
N463
P
R
E
H
G
H
S
N
G
N
R
K
Y
E
S
Dog
Lupus familis
XP_536939
725
81954
N463
P
R
E
H
G
H
S
N
G
N
R
K
Y
E
S
Cat
Felis silvestris
Mouse
Mus musculus
O08796
724
81720
N462
P
R
E
H
G
H
S
N
G
N
R
R
H
E
S
Rat
Rattus norvegicus
P70531
724
81471
N462
P
R
E
H
G
H
S
N
G
N
R
R
P
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508333
641
73286
L404
V
S
V
D
K
W
N
L
Y
N
A
S
R
L
H
Chicken
Gallus gallus
XP_414920
725
82845
N463
H
R
E
K
G
H
S
N
N
N
R
R
H
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002740
706
80225
S447
G
G
D
S
G
Y
P
S
E
K
R
S
E
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O01991
768
87807
F462
L
R
Q
R
H
D
S
F
R
S
S
V
G
T
Y
Sea Urchin
Strong. purpuratus
XP_788087
683
78401
E433
F
R
L
D
S
E
S
E
S
E
T
L
S
H
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.5
93
N.A.
89.9
90
N.A.
75.3
78.7
N.A.
64.6
N.A.
N.A.
N.A.
38.6
45.5
Protein Similarity:
100
99.5
98.7
96.6
N.A.
94.7
94.3
N.A.
81.9
89.5
N.A.
75.4
N.A.
N.A.
N.A.
56.3
60.6
P-Site Identity:
100
93.3
86.6
86.6
N.A.
73.3
73.3
N.A.
6.6
60
N.A.
13.3
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
100
100
86.6
86.6
N.A.
86.6
80
N.A.
13.3
80
N.A.
26.6
N.A.
N.A.
N.A.
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
19
0
10
0
0
0
0
0
0
0
0
19
% D
% Glu:
0
0
64
0
0
10
0
10
10
10
0
0
10
64
0
% E
% Phe:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
73
0
0
0
37
0
0
0
10
10
0
% G
% His:
10
0
0
55
10
64
0
0
0
0
0
0
19
10
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
0
0
0
10
0
37
0
0
0
% K
% Leu:
10
0
10
0
0
0
0
10
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
46
10
73
0
0
0
0
0
% N
% Pro:
55
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
82
0
10
0
0
0
0
10
0
64
28
10
0
0
% R
% Ser:
0
10
0
10
10
0
82
10
28
10
10
19
10
0
64
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% T
% Val:
10
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
19
10
0
0
0
37
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _